The name Lambrusco is based on grape variety, and Lambrusco wines have been given PDO (Protected Denomination of Origin) status based on variety and method of production. They are produced in several regions in Italy, but mainly in the north including Modena, Reggio Emilia, and Mantua. In this study, 40 PDO Lambrusco wines were collected, 24 from Modena, 10 from Mantua, and 6 from Reggio Emilia. The feasibility of using isotopic ratios of 11B/10B, 87Sr/86Sr, 20yPb/20xPb, 18O/16O, and the elemental concentrations of boron, lead and strontium were determined. After different chemometric analyses, the best differentiation of the PDOs was based mainly on boron and strontium, in terms of concentration and isotopic ratios, and on lead isotopic ratios.
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