analysis (5)

12358146260?profile=RESIZE_584xIn March 2023, Dr Malcolm Burns, Head of the GMO Analytical Unit at the National Measurement Laboratory at LGC presented presented at the International Conference on GMO and New Genomic Techniques on 'Analytical strategies for detection of GMO's and NGT products- status and challenges'. The presentation explored some of the opportunities and challenges for the development of methods for the detection of NGT products.

You can now view Malcolm's presentation here.         
Note: all information given in the presentation was correct at the time of the presentation in March 2023.

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Earlier this year, the Food Standards Agency (FSA) commissioned the UK National Reference Laboratory for GMOs based at LGC (Teddington), to deliver a desk-based review of the current state-of-the-art associated with methods for the potential detection of 12227147085?profile=RESIZE_710x (PBOs) in the food and feed supply chains.

Precision Bred Organisms represent organisms which possess genetic variability resulting from the application of modern biotechnology, which could also have arisen through traditional processes. In March 2023 the Genetic Technology (Precision Breeding) Act was passed in the UK, which brought forward primary legislation to amend the regulatory definition of a Genetically Modified Organism (GMO), to exclude from it those organisms that have genetic changes that could also have arisen through traditional processes.

The report, written by Malcolm Burns and Gavin Nixon, captures use of sector specific terminology and related international developments. A focus is given on the current scope and challenges for the analytical detection of specific DNA sequences alongside supportive traceability tools inclusive of reference materials and databases. The report provides a series of recommendations towards helping develop a framework for the traceability of PBOs as well as some of the future analytical challenges this presents.

The report will be of interest to scientists and analysts involved in developing molecular biology assays for the detection of small DNA sequence changes, government departments and related stakeholders involved in assessing the efficacy of methods for the traceability of PBOs, as well as to a broader audience (e.g., academia, industry, retailers, etc.,) who are interested in some of the scope and challenges that detection of PBOs may present.

The report can be found here and a pdf version here

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An e-seminar covering issues surrounding the use of CBD in food supplements and difficulties likely to be encountered in their analytical testing has been published.

It aims to help manufacturers, suppliers and laboratories understand the issues surrounding the use of cannabidiol, more commonly known as CBD, in food supplements and the difficulties likely to be encountered in testing food supplements containing CBD. The manufacture and supply of food supplements are strictly controlled under food laws, it is therefore important to understand what CBD is and how it is regulated in food products. This presentation focuses on CBD, its chemistry in relation to food supplements and regulatory legislation, as well as considering the analytical aspects of measuring CBD in food supplements.

The e-seminar is intended for individuals working in official control laboratories, the food industry and those involved with the UK official control system.

The production of this e-seminar was co-funded by the UK Department for Environment, Food and Rural Affairs, Defra, the Food Standards Agency, Food Standards Scotland and the Department for Business, Energy and Industrial Strategy, BEIS via the Government Chemist, under the Joint Knowledge Transfer Framework for Food Standards and Food Safety Analysis.

This e-seminar has also been added to the Food Authenticity Network's Training Section, where 12 other authenticity related e-seminars are available.

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Pictured above is Bhavna Parmar of the UK Food Standards Agency with Anne Bridges of AACC International.

The Codex Committee on Methods of Analysis and Sampling (CCMAS) held its 40th Session in Budapest, Hungary, from 27 to 31 May 2019. The Session was attended by 49 Member countries and 1 Member organization and 12 observer organisations.

Selvarani Elahi, representing the UK Government Chemist, attended as part of the UK delegation together with colleagues from the Food Standards Agency and the Association of Public Analysts.

CCMAS considers methods of analysis for Codex standards and testing in relation to international food trade. CCMAS 40 discussed analytical methods for nutritional metals, acid value and free fatty acids in palm oil, milk and milk product commodities, 'gluten free' labelling in products containing cereals, pulses and legumes, and herbs & species. The meeting also received updates from working groups on the revision of three substantive Codex documents: general standard for methods of analysis and sampling, guidelines on measurement uncertainty and guidelines on sampling. Work on these documents continues in order to reach global consensus.

As there is increasing interest in food integrity and food authenticity at Codex, the poster on the Food Authenticity Network attracted attention from delegates. Follow-up discussions are planned with member countries on creating ‘country-specific’ pages on the Food Authenticity Network for their countries in order to create a truly global network. Discussions will also continue with the food industry and observer organisations looking to support the work of the Network.

If you would like further information on supporting the Network, please contact us on Secretary@foodauthenticity.uk.

The Food Authenticity Network is mentioned in the meeting report, which is available from the Codex Alimentarius website.

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IFST has re-written its “Food authenticity testing” Information Statement and split it into two parts:

Food authenticity testing part 1: The role of analysis, which now covers the role of analytical testing within the context of an overall supply chain assurance strategy.

Analytical testing is a valuable tool in the armoury to assure food authenticity but cannot be used to identify every type of food fraud.  It is only one part of an overall strategy to mitigate fraud risk.

Many modern tests are based upon comparing a pattern of measured values in the test sample with patterns from a database of authentic samples. Interpretation is highly dependent on the robustness of the database, and whether it includes all possible authentic variables and sample types. This information may not be released by the laboratory.  Interpretation of results is rarely clear-cut, and analytical results are often used to inform and target further investigation (such as unannounced audits or mass-balance checks) rather than for making a compliance decision.

This paper describes where testing can and cannot be used, and highlights generic issues relating to interpreting food authenticity testing results.

Food authenticity testing part 2: Analytical techniques, which gives describes specific analytical techniques, their applications, strengths and weaknesses.

This paper describes the principles, different configurations, applications, strengths and limitations of some of the more common analytical techniques used in food authenticity testing:
• Mass spectrometry
• Stable isotope mass spectrometry
• DNA analysis
• Nuclear magnetic resonance spectrometry
• Spectroscopy.

Generic strengths and limitations of food authenticity test methods, particularly those relating to methods comparing against reference databases of authentic samples, are discussed in “Food authenticity testing: The role of analysis”. It also describes the difference between targeted and untargeted analysis.

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